헌혈로 인한 인간광우병 발병 사례는 현재까지 영국에서 총 네 건이 발견되었다고 한다.
- 사례 1
- 발견: 2003년 12월
- 헌혈한 사람은 헌혈하고 3년 반 후에 인간광우병(vCJD) 발병
- 헌혈받은 사람은 헌혈받고 6년 반 후에 인간광우병(vCJD) 발병
- 사례 2
- 헌혈한 사람은 헌혈하고 18개월 후에 인간광우병(vCJD) 발병
- 헌혈받은 사람은 헌혈받고 몇개월 후 인간광우병(vCJD) 감염 사실 발견됨. (헌혈받은지 5년 후 vCJD와 관계없는 이유로 사망)
- 사례 3
- 헌혈한 사람은 헌혈하고 20개월 후에 인간광우병(vCJD) 발병
- 헌혈받은 사람은 헌혈받고 후 6년 후에 인간광우병(vCJD) 발병
- 사례 4
- 헌혈한 사람은 헌혈하고 17개월 후에 인간광우병(vCJD) 발병
- 헌혈받은 사람은 헌혈받고 후 8년 반 후에 인간광우병(vCJD) 발병
(원문)
There have been four cases of variant-CJD infection associated with
blood transfusion: three of the four recipients developed symptoms of
vCJD. The first case of vCJD disease associated with blood transfusion
was identified in December 2003. This individual developed vCJD six and
a half years after transfusion of red cells donated by an individual
who developed symptoms of vCJD three and a half years after donation. A
case of vCJD 'infection' was identified a few months later in a
recipient of red cells from a donor who developed symptoms of vCJD 18
months after donation. This second case died from causes unrelated to
vCJD five years after transfusion. Post-mortem investigations found
abnormal prion protein in the spleen and a cervical lymph node, but not
in the brain, and no pathological features of vCJD were found. The
third case developed symptoms of vCJD after 6 years and died 8 years
and 8 months after receiving a transfusion of red blood cells from a
donor who developed vCJD about 20 months after this blood was donated.
The fourth case developed symptoms of vCJD 8.5 years after receiving a
transfusion of red blood cells from a donor who developed vCJD about 17
months after this blood was donated. The same donor donated the
vCJD-implicated blood transfused to the 3rd and 4th cases. All four
cases had received transfusions of non-leucodepleted red blood cells
between 1996 and 1999. (출처:
영국 HPA 웨사이트)